Detalhe da pesquisa
1.
Formation of large oligomers of DOPAL-modified α-synuclein is modulated by the oxidation of methionine residues located at C-terminal domain.
Biochem Biophys Res Commun
; 509(2): 367-372, 2019 02 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30591215
2.
Oligomerization and Membrane-binding Properties of Covalent Adducts Formed by the Interaction of α-Synuclein with the Toxic Dopamine Metabolite 3,4-Dihydroxyphenylacetaldehyde (DOPAL).
J Biol Chem
; 290(46): 27660-79, 2015 Nov 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-26381411
3.
Pitfalls associated with the use of Thioflavin-T to monitor anti-fibrillogenic activity.
Bioorg Med Chem Lett
; 24(14): 3194-8, 2014 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24835632
4.
Alpha-synuclein in Parkinson's disease: a villain or tragic hero? A critical view of the formation of α-synuclein aggregates induced by dopamine metabolites and viral infection.
Expert Rev Neurother
; 23(4): 321-330, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37016954
5.
Molecular insights into human monoamine oxidase (MAO) inhibition by 1,4-naphthoquinone: evidences for menadione (vitamin K3) acting as a competitive and reversible inhibitor of MAO.
Bioorg Med Chem
; 19(24): 7416-24, 2011 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22071524
6.
In vitro neurotoxicity of salsolinol is attenuated by the presynaptic protein α-synuclein.
Biochim Biophys Acta Gen Subj
; 1862(12): 2835-2845, 2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30251672
7.
A Medical Approach to the Monoamine Oxidase Inhibition by Using 7Hbenzo[ e]perimidin-7-one Derivatives.
Curr Top Med Chem
; 17(4): 489-497, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-27558674
8.
Beyond topoisomerase inhibition: antitumor 1,4-naphthoquinones as potential inhibitors of human monoamine oxidase.
Chem Biol Drug Des
; 83(4): 401-10, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24165164
9.
α-Synuclein as an intrinsically disordered monomer--fact or artefact?
FEBS J
; 280(19): 4915-27, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-23927048
10.
Vitamins K interact with N-terminus α-synuclein and modulate the protein fibrillization in vitro. Exploring the interaction between quinones and α-synuclein.
Neurochem Int
; 62(1): 103-12, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-23064431